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KMID : 0377619680150030197
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Korean Jungang Medical Journal
1968 Volume.15 No. 3 p.197 ~ p.202
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A Case of Mycosis Fungoides
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高一香/Ko, Ill hyang
金箕洪/高光烈/金世煥/許沅/池貞姬/Kim, Ki Hong/Ko, Kwang Yul/Kim, Se Whan/Huh, Won/Chee, Chung Hee
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Abstract
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This is a case of 27 year old male who had had severe pruritis with marked exfoliative dermatitis of 2 year duration, followed by skin tumor and, finally, visceral involvement. The death was complicated by bilateral bronchopneumonia with asperosilosis. In addition to clinical observation, characteristic histologic finding of cellular multiplicity with atypical histiocytes, immature reticulum cells and Pautrier´s microab- scesses in the skin & axillary node serially biopsied made confirmed diagnosis of mycosis fungoides. At autopsy, multiple involvement of lymph node, predominantly periaortic nodes, kidneys, adrenals, stomach and pancreas was disclosed. Histopathologic picture of these, without doubt, was that of reticulum cell sarcoma but neither picture of reticulum cell sarcoma nor mycosis fungoides were observed in the skin lesion at autopsy.
As clearly demonstrated in this case, the striking similarities of viseral metastasis in mycosis fungoides to lesions of other lymphomas pose quetion of common etiology, pathogenesis and host response. However, it would appear that mycosis fungoides is distinguishable early in the disease from other malignant lymphoma solely on the basis of its characteristic clinical course and cutaneous histopathology.
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